MIBIOTRACE
Preclinical Molecular Imaging

Accelerating Drug Validation with Quantitative Imaging

Quantitative preclinical molecular imaging services that accelerate drug validation, providing the evidence needed to de-risk drug development.

Fig. 01 — Whole-body PET/MRI, rat glioblastoma model

Quantitative Preclinical Imaging

In Vivo Validation·Target Engagement·Whole-Body Biodistribution·De-risking Drug Development
Services

Three critical questions, answered in vivo.

Customized preclinical imaging studies for a comprehensive characterization of your drug candidate.

01
BIOPET4D

Where does the drug go?

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Track your drug throughout the body with quantitative, longitudinal imaging to characterize its biodistribution and pharmacokinetics, and accurately estimate target engagement in vivo.

  • Target engagement
  • Whole body biodistribution
  • Pharmacokinetics
02
BIOPERM

How long does it stay?

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Determine how long your therapeutic or drug delivery system remains at the target site, providing quantitative evidence of biological permanence.

  • Biopermanence
  • Residence time
  • Clearance rate
03
VIEW-RESPONSE

Is it working?

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Assess therapeutic efficacy in vivo through quantitative PET biomarkers, enabling early assessment of biological response.

  • Treatment response
  • PET biomarkers
  • Pharmacodynamics
TheraPET4D®

Quantitative Molecular Imaging

TheraPET4D® automates whole-body quantification of drug delivery, target binding and washout kinetics, providing comprehensive quantitative and accurate insights for novel biological therapeutics.

In vivo
Quantitative metrics
90%
Reduction in animals used
4D
Total-body
Fig. 02 — Whole-body washout, 0–216 h
How we work

Validate your candidates. Select your lead.

Compare drug candidates to identify the best lead while reducing development time and costs.

See the full workflow →

Labeling

Your therapeutic candidate is labeled using methods that preserve its biological properties and behavior, ensuring representative in vivo performance.

In vivo imaging

Longitudinal whole-body PET imaging captures the in vivo distribution and behavior of your therapeutic over time.

Image analysis & Quantification

TheraPET4D® converts imaging data into quantitative biodistribution and pharmacokinetic profiles, enabling accurate estimation of drug delivery, target engagement and clearance across tissues of interest.

Data package

A comprehensive report providing the quantitative evidence needed to support confident go/no-go decisions before clinical development.

Facilities

World-class molecular imaging infrastructure.

MIBIOTRACE provides access to an integrated preclinical imaging ecosystem, combining radiochemistry, multimodal imaging and quantitative analysis within a single workflow.

Radiopharmacy laboratory
Labeling procedures
Image acquisition
PET · PET/CT · PET/MRI · SPECT/CT
Animal facilities
Direct access to animal models
Fig. 03 — PET/MRI BIOSPEC 3T
Team

Meet the team behind the company.

The MIBIOTRACE founding team

Validate your candidate.

Book a technical consultation to explore how quantitative molecular imaging can accelerate your drug development.

info@mibiotrace.com · (+34) 661 625 017 · Santiago de Compostela